2014 Fiscal Year Final Research Report
Bone regeneration by combination with human iPS cells and FGF18 in bone microenvironment-imitated Scaffold
Project/Area Number |
25893157
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Research Category |
Grant-in-Aid for Research Activity Start-up
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Allocation Type | Single-year Grants |
Research Field |
Surgical dentistry
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Research Institution | The University of Tokushima |
Principal Investigator |
KOBAYASHI Masako 徳島大学, ヘルスバイオサイエンス研究部, 助教 (90706954)
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Project Period (FY) |
2013-08-30 – 2015-03-31
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Keywords | iPS細胞 / 骨再生 / FGF / スキャフォールド |
Outline of Final Research Achievements |
We focused on human induced Pluripotent Stem (iPS) cells, Fibroblast growth factors, and carbonate apatite as a scaffold in order to realize ideal bone tissue formation for bone regenerative medicine. Implantation of iPS cells with either carbonate apatite granules, calcium carbonate granules, or β-TCP granules to nude mice showed that bone like-structure surrounding the granules could be observed in carbonate apatite group and calcium carbonate group.
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Free Research Field |
口腔外科
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