Basic research for the collaterogenesis in coronary circulation

2014 Fiscal Year Final Research Report

• Project/Area Number: 25893187
• Research Category: Grant-in-Aid for Research Activity Start-up
• Allocation Type: Single-year Grants
• Research Field: Cardiovascular medicine
• Research Institution: Kumamoto University
• Principal Investigator: ARIMA Yuichiro 熊本大学, 医学部附属病院, 助教 (60706414)
• Project Period (FY): 2013-08-30 – 2015-03-31
• Keywords: 側副血行路

Outline of Final Research Achievements

We developed two techniques to visualize the coronary architecture. The micro X-ray CT enabled to understand whole architecture of the coronary vasculature. Bi-phasic endothelial labeling distinguished open and close coronary microcirculation in coronary ligated mice.
Furthermore, to understand the coronary homology between species, we analyze the anatomical characteristics in urodele amphibia. Compare to mammals, urodele coronary circulation are quite few on the surface of ventricle. However, conal region was covered by rich vascular network. And the drainage vessel connected to the sinus venosus. These findings were reported on the 78th and 79th Japanese cardiovascular society annual meeting.

Free Research Field

循環器内科学