2014 Fiscal Year Final Research Report
developing a novel strategy for preventing local recurrence of human glioma with human primary xenografts
| Project/Area Number |
25893188
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| Research Category |
Grant-in-Aid for Research Activity Start-up
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| Allocation Type | Single-year Grants |
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| Research Field |
Neurosurgery
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| Research Institution | Kumamoto University |
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Principal Investigator |
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| Research Collaborator |
ANAI Shigeo 熊本大学, 医学部附属病院, 特任助教
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| Project Period (FY) |
2013-08-30 – 2015-03-31
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| Keywords | 悪性グリオーマ / ドラッグデリバリーシステム / フィブリン糊 / 局所治療 / 初代培養株 / テモゾロミド |
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| Outline of Final Research Achievements |
The purpose of this project is to develop a novel strategy for preventing local recurrence of malignant glioma, because it is usually difficult due to blood-brain barrier.
I investigated that local administration of high concentration of temozolomide with fibrin glue could prevent tumor growth of primary malignant glioma xenografts derived from human glioblastoma.
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| Free Research Field |
脳腫瘍
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