Elucidation of palatal process fusion mechanism by estrogen receptor expression

2014 Fiscal Year Final Research Report

• Project/Area Number: 25893271
• Research Category: Grant-in-Aid for Research Activity Start-up
• Allocation Type: Single-year Grants
• Research Field: Surgical dentistry
• Research Institution: Aichi Gakuin University
• Principal Investigator: KATO Tomoki 愛知学院大学, 歯学部, 非常勤助教 (00712803)
• Project Period (FY): 2013-08-30 – 2015-03-31
• Keywords: 口蓋裂 / エストロゲンレセプター / 予防

Outline of Final Research Achievements

A study was planned for the purpose of clarifying a cleft palate and the relations of the estrogen receptor by examining an expression of estrogen receptor state of the palatal part of the palatal forming phase using the A/J strain mouse which is an animal model with spontaneous cleft lip and/or palate
The expression of estrogen receptor α did not accept it to a mouse embryonic palatal part of the palatal forming phase.The number of the samples is increased, and also the immunostaining of other receptors such as ER β is performed, and examination is going to be performed in future.

Free Research Field

口腔外科学