2017 Fiscal Year Final Research Report
Traslational study of vagus nerve stimulation
| Project/Area Number |
26242040
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| Research Category |
Grant-in-Aid for Scientific Research (A)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Biomedical engineering/Biomaterial science and engineering
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| Research Institution | The University of Tokyo |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
川合 謙介 自治医科大学, 医学部, 教授 (70260924)
國井 尚人 東京大学, 医学部附属病院, 助教 (80713940)
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| Project Period (FY) |
2014-04-01 – 2018-03-31
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| Keywords | 脳 / 神経活動 / 電極 |
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| Outline of Final Research Achievements |
Vagus nerve stimulation (VNS) is a palliative treatment of refractory epilepsy. VNS stimulates left vagus nerves intermittently with chronically implanted cuff electrodes. While VNS is generally recognized as being effective for inhibition of epileptic seizure, the mechanism of action still remains unknown. In the present study, we carried out both animal experiments and clinical studies to elucidate how VNS affects the neural activity in the cerebral cortex, which might modify higher-order brain functions such as perception, cognition, learning and memory as well as epileptic pathology.
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| Free Research Field |
神経工学
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