Development of Innovative Synthetic Reactions Based on Diverse Reactivity of Group 6 and 7 Metals and their Complexes

2017 Fiscal Year Final Research Report

• Project/Area Number: 26248030
• Research Category: Grant-in-Aid for Scientific Research (A)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Synthetic chemistry
• Research Institution: Okayama University
• Principal Investigator: TAKAI KAZUHIKO 岡山大学, 自然科学研究科, 教授 (00144329)
• Co-Investigator(Kenkyū-buntansha): 村井 征史 岡山大学, 自然科学研究科, 助教 (40647070) ; 浅子 壮美 岡山大学, 自然科学研究科, 助教 (80737289)
• Project Period (FY): 2014-04-01 – 2018-03-31
• Keywords: クロム / レニウム / モリブデン / gem-二金属錯体 / anti-Markovnikov付加 / 脱酸素反応 / 均一系錯体 / 触媒反応

Outline of Final Research Achievements

Through this research, we tried to clarify the features of the group 6-7 metals, especially unknown and useful reactivities for organic synthesis. We have found the following synthetic reactions by using the metal complexes. (1) Isolation of silyl-substituted gem-dichromiomethane (and gem-dizinciomethane) complexes and examination of the catalytic reactivity of the isolated complexes toward olefins and carbonyl compounds; (2) Intermolecular anti-Markovnivov addition of carbon nucleophiles by generation of rhenium-alkylidene complexes from terminal alkynes; (3) Molybdenum-catalyzed hydrosilylation of allenes and deoxygenation of epoxides; (4) Novel bismuth-catalyzed electrophilic C-C bond formation and etherification of phenolic hydroxy groups.

Free Research Field

有機合成化学、有機金属化学