2016 Fiscal Year Final Research Report
High sensitive bio-fluorometric gas sensors using NADH-dependent enzymes catalyzing odorous chemicals
| Project/Area Number |
26280053
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Partial Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Perceptual information processing
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| Research Institution | Tokyo Medical and Dental University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
當麻 浩司 東京医科歯科大学, 生体材料工学研究所, 助教 (40732269)
荒川 貴博 東京医科歯科大学, 生体材料工学研究所, 講師 (50409637)
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Keywords | 生化学式蛍光ガスセンサ / NADH / 脱水素酵素 / 還元酵素 / 光計測 |
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| Outline of Final Research Achievements |
Several biochemical gas sensors were developed using an NADH fluorometric unit with a UV-LED excitation and several dehydrogenase enzymes for high sensitive detection of odorous chemicals. As the results, the sensors allowed to monitor the concentration of volatile chemicals (nonenal by ALDH, acetaldehyde by ADH and formaldehyde by FALDH, respectively), thus showing the possibility of novel artificial nose.
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| Free Research Field |
情報学
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