2016 Fiscal Year Final Research Report
Microbial production of elastic polymers with ordered structure
| Project/Area Number |
26281043
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Partial Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Environmental conscious materials and recycle
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| Research Institution | Hokkaido University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
大井 俊彦 北海道大学, 工学(系)研究科(研究院), 准教授 (40223713)
田口 精一 北海道大学, 工学(系)研究科(研究院), 教授 (70216828)
佐藤 敏文 北海道大学, 工学(系)研究科(研究院), 教授 (80291235)
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Keywords | バイオベースプラスチック / 微生物合成 / 生分解性材料 |
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| Outline of Final Research Achievements |
Microbial polyesters are useful material, which are produced from renewable biomass. For the practical use of the material, polymer properties are critical factors. It is well-known that microbial copolyesters are random polymer. However, we found a condition that generated copolymer with low randomness. This study addressed optimization of the polymer production, structure and property analysis, and kinetic analysis of relevant enzymes. As the results, the copolymer, in which the monomer composition was regulated, was successfully synthesized with good yield. The copolymers exhibit transparent and flexible properties. The enzymatic activity of relevant enzymes accounted for the intracellular intermediate levels. Overall, the study contributed to the significantly improved the efficiency of the polymer production system, and provided insight into the mechanism of the polymer synthesis.
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| Free Research Field |
生物化学
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