Development of regenerative rehabilitation as the fourth element of regenerative medicine

2016 Fiscal Year Final Research Report

• Project/Area Number: 26282154
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Partial Multi-year Fund
• Section: 一般
• Research Field: Rehabilitation science/Welfare engineering
• Research Institution: Kyoto University
• Principal Investigator: Aoyama Tomoki 京都大学, 医学(系)研究科(研究院), 准教授 (90378886)
• Co-Investigator(Kenkyū-buntansha): 黒木 裕士 京都大学, 医学(系)研究科(研究院), 教授 (20170110)
• Project Period (FY): 2014-04-01 – 2017-03-31
• Keywords: 再生医療 / リハビリテーション / 関節軟骨再生 / エクササイズ / 物理療法

Outline of Final Research Achievements

Cell, scaffold, and nutrition are the three essential elements of regenerative medicine. However, these elements focus only on cells or tissues, but not organs and individuals. The purpose of this study was to develop and show the usefulness of rehabilitation resource to promote the regenerative effect of regenerative medicine. The osteochondral defect on rat knee joint was additively regenerated by mesenchymal stromal cell transplantation when combined with exercise or low-intensity pulsed ultrasonographic stimulation. These data suggest that rehabilitation programs can be the fourth element to promote the effect of regenerative medicine.

Free Research Field

再生医学