2016 Fiscal Year Final Research Report
Creation of agents that selectively photo-degrade certain proteins and oligosaccharides and its application to control of cell functions
| Project/Area Number |
26282212
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Partial Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Biomolecular chemistry
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| Research Institution | Keio University |
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Principal Investigator |
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Keywords | 生物活性分子 / 分子設計 / 合成 / タンパク / 糖 / 光分解 / 細胞 / 生体機能光制御分子 |
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| Outline of Final Research Achievements |
Several agents, that target-selectively photo-degrade certain disease-related proteins and oligosaccharides, were designed and synthesized. Furthermore, it was found the agents thus developed work not only in test tube but also in disease-related cells. From these studies, a new approach for the design of light-activated and molecular-targeted medicines has been established.
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| Free Research Field |
分子生命化学
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