2016 Fiscal Year Final Research Report
Molecular structure mechanism of caveolae membrane coats
Project/Area Number |
26286027
|
Research Category |
Grant-in-Aid for Scientific Research (B)
|
Allocation Type | Partial Multi-year Fund |
Section | 一般 |
Research Field |
Nanobioscience
|
Research Institution | Kyoto University |
Principal Investigator |
MORONE NOBUHIRO 京都大学, 物質-細胞統合システム拠点, 教授 (50399680)
|
Project Period (FY) |
2014-04-01 – 2017-03-31
|
Keywords | 1分子科学 / 細胞膜 / カベオラ / エンドサイトーシス |
Outline of Final Research Achievements |
Cavoelae are striated membrane invagination (around 70nm in diameter) at the plasma membrane except for neurons, which involved in endocytosis, transcytosis, and fatty acid uptake. Freeze-replica electron microscopy would be useful for caveolar analysis due to their fine structures on the cytoplasmic surface of plasma membrane. This research focused caveolar base structures by electron microscopy.
|
Free Research Field |
Structrual cell biology
|