Development of high power THz TDS system for investigation of protein dynamics

2016 Fiscal Year Final Research Report

• Project/Area Number: 26286083
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Partial Multi-year Fund
• Section: 一般
• Research Field: Quantum beam science
• Research Institution: National Institute of Advanced Industrial Science and Technology
• Principal Investigator: Kuroda Ryunosuke 国立研究開発法人産業技術総合研究所, 先端オペランド計測技術オープンイノベーションラボラトリ, ラボチーム長 (70350428)
• Co-Investigator(Kenkyū-buntansha): 田中 真人 国立研究開発法人産業技術総合研究所, 分析計測標準研究部門, 主任研究員 (30386643) ; 平 義隆 国立研究開発法人産業技術総合研究所, 分析計測標準研究部門, 研究員 (60635803) ; 坂上 和之 早稲田大学, 高等研究所, 助教 (80546333)
• Project Period (FY): 2014-04-01 – 2017-03-31
• Keywords: テラヘルツ / 光源技術 / 超短パルス電子ビーム / 分光技術 / 水和タンパク質 / 高性能レーザー / 時間領域分光

Outline of Final Research Achievements

We have developed the high-power THz spectroscopy system for investigation of the hydrated protein on the basis of S-band compact electron linac. We have also performed the high-power THz-TDS system with EO sampling method. In case of the THz spectroscopy with THz band-pass filters (0.1-1.5 THz), the absorption coefficient measurements of the liquid protein solutions were successfully carried out with different concentrations. As a result, the hydration layer was estimated by assuming the hydration model.

Free Research Field

量子ビーム科学