2016 Fiscal Year Final Research Report
Signalling Mechanism of Autophagy Regulation by Nutrients and Food Components : Its Diversity and Anti-aging.
| Project/Area Number |
26292066
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Partial Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Food science
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| Research Institution | Niigata University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
藤村 忍 新潟大学, 自然科学系, 准教授 (20282999)
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Keywords | オートファジー / シグナリング / 抗加齢 / アミノ酸 / サーチュイン |
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| Outline of Final Research Achievements |
In order to contribute to anti-aging through autophagy regulation by nutrition, we searched nutrients, especially amino acids and antioxidants, and rice protein as a possible regulatory food factors of autophagy, and investigated their regulatory mechanisms, i.e., signaling mechanisms at the formation step of autophagosome, the transcription step, and the relationship with aging gene, SIRT1 including acetylation. These findings will give the evidence for food functions on elderly people.
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| Free Research Field |
農芸化学・食品科学
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