Study of ion transporters involved in acclimation of teleost fishes to fresh water and seawater

2017 Fiscal Year Final Research Report

• Project/Area Number: 26292113
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Partial Multi-year Fund
• Section: 一般
• Research Field: Aquatic life science
• Research Institution: Tokyo Institute of Technology
• Principal Investigator: Kato Akira 東京工業大学, バイオ研究基盤支援総合センター, 准教授 (40311336)
• Project Period (FY): 2014-04-01 – 2017-03-31
• Keywords: イオン輸送体 / 真骨魚 / 淡水順応 / 海水順応 / 水電解質代謝 / 上皮輸送 / 腎臓 / 比較生理学

Outline of Final Research Achievements

The genome of teleost fishes encodes more than a thousand of membrane transport proteins such as transporters, channels, and pumps. Some of these transporters are expressed in the epithelia of the gill, intestine, and kidney and are responsible for the osmoregulation and the body-fluid homeostasis of teleost fishes in fresh water and seawater environments. However, the activities of these transporters are not well characterized in vitro. In the present study, we analyzed the function of these transporters by using electrophysiological techniques to clarify novel branchial and renal mechanisms for the freshwater and seawater acclimation.

Free Research Field

魚類生理学