Roles of neuropeptides in the immune system of teleost fish

2016 Fiscal Year Final Research Report

• Project/Area Number: 26292115
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Partial Multi-year Fund
• Section: 一般
• Research Field: Aquatic life science
• Research Institution: Kitasato University
• Principal Investigator: Amano Masafumi 北里大学, 海洋生命科学部, 教授 (10296428)
• Co-Investigator(Kenkyū-buntansha): 高橋 明義 北里大学, 海洋生命科学部, 教授 (10183849) ; 筒井 繁行 北里大学, 海洋生命科学部, 講師 (20406911) ; 水澤 寛太 北里大学, 海洋生命科学部, 准教授 (70458743) ; 阿見彌 典子 北里大学, 海洋生命科学部, 講師 (20588503)
• Project Period (FY): 2014-04-01 – 2017-03-31
• Keywords: 魚類 / 免疫系 / 脳ホルモン / 腎臓 / 脾臓 / 白血球

Outline of Final Research Achievements

To gain a better understanding of the interaction between endocrine and immune systems in fish, we examined whether some neuropeptide hormones, such as gonadotropin-releasing hormone (GnRH), corticotropin-releasing peptide (CRH) and prolactin-releasing peptide (PrRP), exist in the immune organs of several teleost fishes by molecular biological technique and immunocytochemistry. These neuropeptides were detected in the immune organs (blood cells, kidney, and spleen) of teleost fishes such as rainbow trout, goldfish, common carp, Japanese eel, tiger puffer, and Japanese flounder. These results suggest that the interaction exists between endocrine and immune systems in teleost fish.

Free Research Field

水族生理学