2016 Fiscal Year Final Research Report
Aging research using telomere age
| Project/Area Number |
26310106
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (B)
|
| Allocation Type | Partial Multi-year Fund |
|---|
| Section | 特設分野 |
|---|
| Research Field |
Neo-Gerontology
|
|---|
| Research Institution | Hiroshima University |
|---|
Principal Investigator |
|
|---|
| Project Period (FY) |
2014-07-18 – 2017-03-31
|
| Keywords | テロメア / Ｇテール / 加齢 / 遺伝子年齢 / 健康寿命 / 未病 |
|---|
| Outline of Final Research Achievements |
We discovered a non-invasive surrogate marker that could predict an increased risk of future cardiovascular disease, stroke, dementia, and death. Telomere G-tail length is associated with age and vascular risk factors, and might be superior to total telomere length as a marker of endothelial dysfunction and ARWMC severity. Telomere G-tail length might be a promising biomarker of age-associated disease.
|
| Free Research Field |
テロメア、エクソソーム、がん、マイクロRNA
|
