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2016 Fiscal Year Research-status Report

Fast Graph Algorithms for Phylogenetics

Research Project

Project/Area Number 26330014
Research InstitutionKyoto University

Principal Investigator

ジャンソン ジェスパー  京都大学, 白眉センター, 特定准教授 (60536100)

Project Period (FY) 2014-04-01 – 2018-03-31
Keywordsalgorithm / computational complexity / phylogenetic tree / consensus tree
Outline of Annual Research Achievements

We developed new algorithms that are faster than all the previously known ones for a number of popular types of consensus trees (majority rule consensus tree, loose consensus tree, greedy consensus tree, R* consensus tree, etc.). We also proved that two variants of the local consensus tree problem in which the goal is to construct a minimal phylogenetic tree (where "minimal" means either having the smallest possible number of internal nodes or the smallest possible number of resolved triplets) that contains every resolved triplet present in all of the input trees trees are NP-hard and gave exact, exponential-time solutions for both problems. The second variant generalizes the RV-II tree, introduced by Kannan, Warnow, and Yooseph in 1998. Furthermore, for the rooted triplet consistency problem, we characterized how the computational complexity changes under various restrictions and obtained a linear-time algorithm for dense inputs with no forbidden resolved triplets.

Current Status of Research Progress
Current Status of Research Progress

2: Research has progressed on the whole more than it was originally planned.

Reason

In FY2016, we published several peer-reviewed conference papers and journal articles related to the topics in the grant application. In particular, our main results on consensus trees appeared in Journal of the ACM, one of the top journals in our field. We are currently working on fast algorithms for computing the rooted triplet distance between two phylogenetic networks; for the special case where all cycles in the underlying undirected graphs are disjoint, we have recently discovered a method that can do it in subquadratic time by transforming the input so that the answer can be obtained by applying an existing algorithm for the simpler case of two phylogenetic trees a constant number of times.

Strategy for Future Research Activity

As planned.

Causes of Carryover

The flight to Copenhagen was cheaper than expected.

Expenditure Plan for Carryover Budget

To buy some equipment for backups.

  • Research Products

    (14 results)

All 2017 2016 Other

All Journal Article (5 results) (of which Int'l Joint Research: 5 results,  Peer Reviewed: 5 results,  Open Access: 3 results,  Acknowledgement Compliant: 5 results) Presentation (1 results) Book (5 results) Remarks (3 results)

  • [Journal Article] Determining the Consistency of Resolved Triplets and Fan Triplets2017

    • Author(s)
      J. Jansson, A. Lingas, R. Rajaby, and W.-K. Sung
    • Journal Title

      Lecture Notes in Computer Science

      Volume: 10229 Pages: 1-17

    • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Improved Algorithms for Constructing Consensus Trees2016

    • Author(s)
      J. Jansson, C. Shen, and W.-K. Sung
    • Journal Title

      Journal of the ACM

      Volume: 63 Pages: 28

    • DOI

      10.1145/2925985

    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Faster Algorithms for Computing the R* Consensus Tree2016

    • Author(s)
      J. Jansson, W.-K. Sung, H. Vu, and S.-M. Yiu
    • Journal Title

      Algorithmica

      Volume: 76 Pages: 1224-1244

    • DOI

      10.1007/s00453-016-0122-2

    • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] A More Practical Algorithm for the Rooted Triplet Distance2016

    • Author(s)
      J. Jansson and R. Rajaby
    • Journal Title

      Journal of Computational Biology

      Volume: 24 Pages: 106-126

    • DOI

      10.1089/cmb.2016.0185

    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Minimal Phylogenetic Supertrees and Local Consensus Trees2016

    • Author(s)
      J. Jansson and W.-K. Sung
    • Journal Title

      LIPIcs

      Volume: 58 Pages: 53:1-53:14

    • DOI

      10.4230/LIPIcs.MFCS.2016.53

    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Presentation] Minimal Phylogenetic Supertrees and Local Consensus Trees2016

    • Author(s)
      Jesper Jansson
    • Organizer
      MFCS 2016
    • Place of Presentation
      Krakow, Poland
    • Year and Date
      2016-08-22
  • [Book] Algorithms for Combining Rooted Triplets into a Galled Phylogenetic Network [chapter in Encyclopedia of Algorithms]2016

    • Author(s)
      J. Jansson and W.-K. Sung
    • Total Pages
      48-52
    • Publisher
      Springer Science+Business Media New York
  • [Book] Directed Perfect Phylogeny (Binary Characters) [chapter in Encyclopedia of Algorithms]2016

    • Author(s)
      J. Jansson
    • Total Pages
      553-556
    • Publisher
      Springer Science+Business Media New York
  • [Book] Maximum Agreement Supertree [chapter in Encyclopedia of Algorithms]2016

    • Author(s)
      J. Jansson and W.-K. Sung
    • Total Pages
      1224-1227
    • Publisher
      Springer Science+Business Media New York
  • [Book] Perfect Phylogeny (Bounded Number of States) [chapter in Encyclopedia of Algorithms]2016

    • Author(s)
      J. Jansson
    • Total Pages
      1550-1553
    • Publisher
      Springer Science+Business Media New York
  • [Book] Phylogenetic Tree Construction from a Distance Matrix [chapter in Encyclopedia of Algorithms]2016

    • Author(s)
      J. Jansson
    • Total Pages
      1564-1567
    • Publisher
      Springer Science+Business Media New York
  • [Remarks] Jesper Jansson's webpage:

    • URL

      http://sunflower.kuicr.kyoto-u.ac.jp/~jj/

  • [Remarks] FACT: Fast Algorithms for Consensus Trees:

    • URL

      http://compbio.ddns.comp.nus.edu.sg/~consensus.tree/

  • [Remarks] CPDT-dist:

    • URL

      http://sunflower.kuicr.kyoto-u.ac.jp/~jj/Software/CPDT-dist.html

URL: 

Published: 2018-01-16  

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