The development of inhibition technology against biofilm formation and biofouling with controlling the activities of complex microbes

2017 Fiscal Year Final Research Report

• Project/Area Number: 26340068
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Modeling and technologies for environmental conservation and remediation
• Research Institution: Utsunomiya University
• Principal Investigator: IKEDA TSUKASA 宇都宮大学, 工学(系)研究科(研究院), 教授 (40151295)
• Project Period (FY): 2014-04-01 – 2018-03-31
• Keywords: バイオフィルム / バイオファウリング / 複合共生微生物 / Quorum Sensing / Quorum Quenching / アシル化ホモセリンラクトン / 活性汚泥

Outline of Final Research Achievements

The inhibition technology against biofilm formation and biofouling has been developed with controlling the activities of complex microbes.
N-acyl homoserine lacton (AHL), a signal molecule of quorum sensing in gram negative bacteria, producing bacteria and also AHL degradation bacteria were isolated from the same biofilm sample. Bacterial biofilm formation and biofouling are regulated by QS. For these reasons, quorum quenching (QQ) bacteria and enhancement there QQ activities should be useful for inhibition of biofilm formation and biofouling under complex microbes condition.
Moreover, several QQ techniques to inhibit biofilm formation have been developed.

Free Research Field

生物有機化学、