Instruction effect of the oral immunization generosity with the allergenic oral administration in the allergic model mouse

2016 Fiscal Year Final Research Report

• Project/Area Number: 26350137
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Eating habits
• Research Institution: Mukogawa Women's University
• Principal Investigator: Takahashi Kyoko 武庫川女子大学, 生活環境学部, 教授 (50175428)
• Project Period (FY): 2014-04-01 – 2017-03-31
• Keywords: 食物アレルギー / 卵アレルギー / 低減化ボーロ / アレルギーモデルマウス

Outline of Final Research Achievements

As a result of having made rapid acquired tolerance on an allergic model mouse in 2014, the allergic symptom was not improved and showed a tendency to aggravation in some biomarker. As a result of having taken long-term oral immunization therapy using the antigen addition feed to an allergic model mouse in 2915~2016, 1% antigen addition feed made an allergy symptom relieved. Acquired tolerance determined what was induced as a result that children with serious egg allergy received the egg bolo long-term oral immunization therapy that we used a low allergen (they performed it through study period) when we continued an antigen even if it was low capacity and took it in.

Free Research Field

食生活