Approach from physiological functions in mechanisms of stress, quality and quantity of sleep and sense of well-being.

2017 Fiscal Year Final Research Report

• Project/Area Number: 26350876
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Applied health science
• Research Institution: Prefectural University of Hiroshima
• Principal Investigator: Iida Tadayuki 県立広島大学, 保健福祉学部(三原キャンパス), 教授 (50290549)
• Co-Investigator(Kenkyū-buntansha): 八谷 寛 藤田保健衛生大学, 医学部, 教授 (30324437) ; 伊藤 康宏 藤田保健衛生大学, 保健学研究科, 教授 (40176368) ; 井上 顕 高知大学, 教育研究部医療学系臨床医学部門, 教授 (40469036) ; 巽 あさみ 浜松医科大学, 医学部, 教授 (90298513)
• Project Period (FY): 2014-04-01 – 2018-03-31
• Keywords: 睡眠 / 自律神経活動 / ストレス / u-8-OHdG / u-5-HT / SDS / STAI

Outline of Final Research Achievements

The percentage of people with work- and life-related anxiety, worry, and stress is increasing every year, and it is said to exceed 60%. The relationship between psychological stress and oxidative stress has become a focus of interest, and the mechanism by which psychological stress increases reactive oxygen species (ROS) is slowly being elucidated. This study focused on [Association between the Profile of Mood States and Autonomic Nervous System Activity during Sleep] and [Effects of psychological stress on the urine 8-hydroxy-deoxyguanosine levels in young female students, taking into account the menstrual cycle]. Mood changes showed an association with sympathetic and parasympathetic nervous system activities during sleep, suggesting the possibility of these activities influencing moods.This study also showed that U8-OHdG levels increased with the psychological stress of a national license examination.

Free Research Field

応用健康科学