2016 Fiscal Year Final Research Report
Effects of the intramuscula fat on insulin resistance
| Project/Area Number |
26350883
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Applied health science
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| Research Institution | Utsunomiya University |
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Principal Investigator |
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| Co-Investigator(Renkei-kenkyūsha) |
MORI YUTAKA 東京慈恵会医科大学, 医学部, 教授 (30220031)
KUROKAWA NAOYUKI 宮城教育大学, 教育学部, 准教授 (30431505)
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Keywords | 筋内脂肪 / 内臓脂肪面積 / 最大酸素摂取量 / インスリン抵抗性 / 運動習慣 / CT値 |
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| Outline of Final Research Achievements |
Intramuscular fat has been reported as a factor causing insulin resistance (IR) in obesity. Skeletal muscle attenuation (CT value) determined by computed tomography is associated with skeletal muscle fat content. This study attempted to calculate HOMA-R, an indicator of IR from the amount of skeletal muscle CT values. In addition, we examined the relationship between insulin resistance, exercise habits, and maximum oxygen uptake. The subjects were 45 healthy athletes and 46 non-athletes at our university. Skeletal muscle CT values were measured at the following 5 points. A significant relationship was observed between VO2max and both HOMA-R and VFA, but was no significant relationship between skeletal muscle CT value and either HOMA-R or VFA. However, individuals engaged in regular endurance exercise training had higher muscular fat despite being markedly insulin sensitive. Higher muscular fat of long distance runner is considered that does not cause IR.
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| Free Research Field |
健康科学
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