Conversion of Dinitrogen to Organo-Nitrogen Compounds by Multimetallic Hydride Complexes

2016 Fiscal Year Final Research Report

• Project/Area Number: 26410082
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Inorganic chemistry
• Research Institution: Institute of Physical and Chemical Research
• Principal Investigator: SHIMA Takanori 国立研究開発法人理化学研究所, 侯有機金属化学研究室, 専任研究員 (60391976)
• Project Period (FY): 2014-04-01 – 2017-03-31
• Keywords: 窒素分子活性化 / チタンヒドリド錯体 / ニトリド錯体 / ニトリル / 酸塩化物

Outline of Final Research Achievements

At present, ammonia, produced by the Haber-Bosch process, is the only nitrogen source for the industrial preparation of nitrogen-containing organic products. Although the activation and functionalization of N2 under milder conditions have received much recent interest, studies on the direct use of N2 as a feedstock for organic synthesis are still in their infancy.
We have found that the titanium diimide/dinitride complex, formed by activation of N2 with H2 and the titanium trialkyl complex, served as a unique platform for the synthesis of nitriles through reaction with acid chlorides. This protocol features simple reaction condition, no requirement for extra reagents, and unprecedented functional group tolerance. 15N-Isotope labeled nitriles can also be efficiently prepared by using the 15N-enriched diimide/dinitride analogue derived from 15N2 gas. The titanium complexes could be recycled by treatment of the crude reaction mixture with HCl.

Free Research Field

有機金属化学