Clarification of "arrested melting behavior" of side chains of one-ring-one-chain type polyrotaxane derivatives

2016 Fiscal Year Final Research Report

• Project/Area Number: 26410130
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Polymer chemistry
• Research Institution: Shinshu University
• Principal Investigator: ARAKI Jun 信州大学, 学術研究院繊維学系, 准教授 (10467201)
• Project Period (FY): 2014-04-01 – 2017-03-31
• Keywords: ポリロタキサン / スライディング・グラフトコポリマー / シクロデキストリン / 一環一置換誘導体 / 束縛融解挙動 / 一置換CD誘導体 / クリックケミストリー / 末端封鎖反応

Outline of Final Research Achievements

A synthetic procedure for a novel polyrotaxane derivative called "one-ring-one-chain type polyrotaxane" was established. Monoazido-alpha-CD was synthesized and purified utilizing reversed phase column chromatography in several gram scale. The obtained monoazido-CD was mixed with terminally aminated PEG to yield an inclusion complex, followed by terminal end-cap reaction with sodium 2,4,6-trinitrobenzene sulfonate to obtain a polyrotaxane with monoazido-CD rings. The obtained polyrotaxane was further subjected to click reactions with mPEG having terminal propargyl groups, obtaining a desired one-ring-one-chain type polyrotaxane. The obtained product indicated a so-called "arrested melting behavior", i.e. a sharp exotherm around the melting temperature of side chain polymers (mPEG2000 in this case) without melting of the whole bulk polymer.

Free Research Field

超分子科学、高分子化学