Separating brain activity from hemodynamic change by analysis of temporal changes in signals of near-infrared spectroscopy

2016 Fiscal Year Final Research Report

• Project/Area Number: 26420403
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Measurement engineering
• Research Institution: Tokyo Metropolitan College of Industrial Technology
• Principal Investigator: Fukuda Keiko 東京都立産業技術高等専門学校, ものづくり工学科, 教授 (70396266)
• Co-Investigator(Renkei-kenkyūsha): SEKIHARA KENSUKE 首都大学東京, システムデザイン学部, 教授 (40326020)
• Research Collaborator: ITO YOSHITOSHI
• Project Period (FY): 2014-04-01 – 2017-03-31
• Keywords: 生体情報・計測 / 近赤外分光法 / 脳機能計測 / 皮膚血流 / NIRS / 医用光工学 / 電気電子計測

Outline of Final Research Achievements

In brain function measurements by near-infrared spectroscopy (NIRS), we focus on the temporal changes in the oxygenated and deoxygenated hemoglobin concentrations and propose an analytical approach to the temporal changes of the hemoglobin concentrations' cross-correlation coefficient in the brain functional signals. The cross-correlation coefficient between the oxygenated and deoxygenated hemoglobin concentrations shows negative values for brain activity and positive values for hemodynamic changes. Experiments with a 16-channel functional NIRS system show that our proposed approach clarifies the interpretation of the measured NIRS signals and it is effective for estimating the influence of hemodynamic change on brain activity.

Free Research Field

工学