2016 Fiscal Year Final Research Report
Analysis of post-traslational modification of GAF1 complex in GA signaling
| Project/Area Number |
26440148
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Plant molecular biology/Plant physiology
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| Research Institution | Hiroshima University |
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Principal Investigator |
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Keywords | 植物ホルモン / 信号伝達 / 転写因子 / 成長生理 |
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| Outline of Final Research Achievements |
Gibberellins (GAs) are essential regulates of plant development, including seed germination, stem elongation and flowering. In GA signaling, DELLA protein are negative regulators and degraded by GA. We identified a DELLA-binding transcription factor GAF1. We found that GAF1 interact with corepressor TOPLESS RELATED (TPR) and that DELLAs and TPR act as coactivator and a corepressor of GAF1, respectively. GA converts the GAF1 complex from transcriptional activator to repressor via degradation of DELLAs. This complex is a major components in GA feedback regulation. We found that post-translational modification of GAF1 complex might be involved in GA signaling.
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| Free Research Field |
生物学・植物生理学・分子生物学
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