Roles of TCP transcription factors in plant development

2016 Fiscal Year Final Research Report

• Project/Area Number: 26440158
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Plant molecular biology/Plant physiology
• Research Institution: Suntory Foundation for Life Sciences
• Principal Investigator: Tomotsugu koyama 公益財団法人サントリー生命科学財団, 生物有機科学研究所・統合生体分子機能研究部, 研究員 (90450668)
• Research Collaborator: Sato Fumihiko ; Takagi Masaru (Ohme Masaru)
• Project Period (FY): 2014-04-01 – 2017-03-31
• Keywords: 植物 / 葉 / シロイヌナズナ / TCP / 転写因子

Outline of Final Research Achievements

This work investigated the gene regulatory mechanism of leaf development in Arabidopsis thaliana. The genetic analysis of miR319 and its target TCP gene families demonstrated the roles of these genes in the formation of leaf serrations and cotyledon boundary. Mutations in MIR319 genes inhibited the formation of leaf serrations and the cotyledon boundary in association with regulator genes of the boundary morphogenesis. In contrast, loss-of-function mutations in these TCP genes induced the formation of serrated leaves in addition to changes in the levels of their downstream gene expression. This works also found that quintuple mutant for class I TCP genes induced irrgularity in its leaf form. Overall, combinations of mutations in TCP transcription factor genes in Arabidopsis thaliana generate various leaf forms.

Free Research Field

植物分子生物学