2016 Fiscal Year Final Research Report
Study on the production of rare disaccharides and rare sugars.
| Project/Area Number |
26450097
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Applied microbiology
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| Research Institution | Kagawa University |
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Principal Investigator |
Takata Goro 香川大学, 国際希少糖研究教育機構, 准教授 (50322722)
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| Co-Investigator(Renkei-kenkyūsha) |
Sakuraba Haruhiko 香川大学, 農学部, 准教授 (90205823)
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Keywords | 希少糖 / D-アロース |
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| Outline of Final Research Achievements |
The objective of this study is the production of D-allose, D-altrose and their disaccharides using biotechnology method.
From the result of this research, we succeeded to mass-production of recombinant D-glucoside 3-dehydrogenase and its crystalization. This enzyme showed the substrate specificity against various disaccharides. By combination of chemical hydrogenation, we achieved to produced various rare sugar containing disaccharide such as 1,4-a-allosylglucose, 1,4-b-allosylglucose, 1,1-a-allosylallose, and 1,4-b-gulosylglucose.
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| Free Research Field |
応用微生物学
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