2016 Fiscal Year Final Research Report
Type IV pilus machinery of Thermus thermophilus
| Project/Area Number |
26450102
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Applied microbiology
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| Research Institution | Tokyo University of Pharmacy and Life Science |
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Principal Investigator |
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| Research Collaborator |
Koike Ayumi (Takeshita Ayumi)
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Keywords | 線毛 / 高度好熱菌 |
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| Outline of Final Research Achievements |
The extreme thermophile Thermus thermophilus produces Type IV pili (T4P) on the cell surface. A gene deletion of a protein found in T4P machinery led to loss of twitching motility and sensitivity to a T4P-dependent phage. The expression of the genes encodeing the structural protein of HB8 in HB27 was not sufficient for twitching motility and infection of T4P-dependent phage. This result suggests that T4P-related function requires other protein(s) in addition to the structural proteins.
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| Free Research Field |
バクテリア遺伝学
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