2016 Fiscal Year Final Research Report
Functional study on heterooligosaccharides focusing on N-acetylamino sugars
| Project/Area Number |
26450166
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Multi-year Fund |
|---|
| Section | 一般 |
|---|
| Research Field |
Food science
|
|---|
| Research Institution | Nihon University |
|---|
Principal Investigator |
|
|---|
| Co-Investigator(Renkei-kenkyūsha) |
ODA Munehiro 日本大学, 生物資源科学部, 教授 (10508691)
|
|---|
| Research Collaborator |
RI Shumou
SHINOZAKI Yuko
TAKAHASHI Narumi
|
|---|
| Project Period (FY) |
2014-04-01 – 2017-03-31
|
| Keywords | 応用生物化学 / 応用酵素学 / 糖質化学 / 機能性オリゴ糖 / 微生物利用学 / タンパク質工学 |
|---|
| Outline of Final Research Achievements |
We synthesized novel N-acetylglucosamine-containing oligosaccharides using several transglycosylation-catalyzing glycosidases, and evaluated their prebiotics effect.
As the results, we succeeded in the synthesis 6 kinds of the oligosaccharides using N-acetylsucrosamine as a low material. Moreover, we found that these oligosaccharides proliferated specific species of Bifidobacteria. These facts indicate the possibility that N-acetylglucosamine-containing oligosaccharides we synthesized in this study become new type of prebiotics.
|
| Free Research Field |
応用生物化学
|
