2016 Fiscal Year Final Research Report
Development of novel cyclization reactions via formation of ruthenacycle intermediate and their application to organic synthesis
| Project/Area Number |
26460002
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Chemical pharmacy
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| Research Institution | Meiji Pharmaceutical University (2015-2016)
Hokkaido University (2014) |
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Principal Investigator |
Saito Nozomi 明治薬科大学, 薬学部, 教授 (80349258)
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Keywords | 環化反応 / ルテニウム / メタラサイクル / アレン / アルキン / 環状化合物 / 天然物合成 / アルカロイド |
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| Outline of Final Research Achievements |
Studies on the development of the novel cyclization reactions via ruthenacyclopentene intermediate formed by oxidative cyclization of allene and alkyne were conducted. Furthermore, we performed synthetic studies on indole alkaloids by using the above our ruthenium-catalyzed cyclization as a key step.
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| Free Research Field |
有機合成化学、有機金属化学
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