Elucidating the mechanism of vascular dysfunction to achieve gender-specific medicine

2016 Fiscal Year Final Research Report

• Project/Area Number: 26460228
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Medical pharmacy
• Research Institution: Nagoya City University
• Principal Investigator: Kikuchi Chigusa 名古屋市立大学, 大学院薬学研究科, 講師 (20444987)
• Project Period (FY): 2014-04-01 – 2017-03-31
• Keywords: 糖尿病 / 性差医療 / 血管障害 / 健診受診 / 検体測定室

Outline of Final Research Achievements

In this study, we examined vascular endothelium function using diabetes model animals and questionnaire on factors of going for a medical checkup for women to clarify the mechanism of vascular endothelium dysfunction mediated by sex difference. In diabetes model female rats, post-occlusive hind limb reactive hyperemia index was decreased as compared with control rats at early stage. As the result of the questionnaire, many women were under stress. It was suggested that especially child rearing and economic factors prevent women from going for a medical checkup.

Free Research Field

医療薬学