2016 Fiscal Year Final Research Report
Objective evaluation of chemotherapy-induced peripheral neuropathy using quantitative pain measurement system
Project/Area Number |
26460230
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Medical pharmacy
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Research Institution | Iwate Medical University |
Principal Investigator |
Sato Junya 岩手医科大学, 薬学部, 講師 (40616413)
|
Project Period (FY) |
2014-04-01 – 2017-03-31
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Keywords | がん化学療法 / 末梢神経障害 / 知覚痛覚定量分析装置 / パクリタキセル / 末梢神経障害質問票(PNQ) |
Outline of Final Research Achievements |
For an evaluation of peripheral neuropathy (CIPN) with the chemotherapy, objectivity may be poor because it is determined by the subjective expression of the patients.We attempted an objective evaluation of paclitaxel-induced CIPN using quantitative pain measurement system (Pain vison®).The pain degree (pain perception current value - smallest perception current level) ÷smallest perception current value×100) at the CIPN development by the medical professional evaluation (CTC-AE) was significantly decreased as compared to that of before chemotherapy initiation.Pain vision might become the noninvasive and convenient objective CIPN detection tool to supplement subjective CIPN evaluation.
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Free Research Field |
臨床薬学(がん化学療法)
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