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2016 Fiscal Year Final Research Report

Proteomic analysis of bile

Research Project

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Project/Area Number 26460426
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Human pathology
Research InstitutionSt. Marianna University School of Medicine (2016)
Kitasato University (2014-2015)

Principal Investigator

Yanagisawa Nobuyuki  聖マリアンナ医科大学, 医学部, 准教授 (80337914)

Co-Investigator(Renkei-kenkyūsha) KODERA YOSHIO  北里大学, 理学部, 准教授 (60265733)
Project Period (FY) 2014-04-01 – 2017-03-31
Keywords胆嚢癌 / 胆嚢炎 / 発癌 / プロテオミクス
Outline of Final Research Achievements

The bile and tissue samples including 204 cases of chronic cholecystitis, 30 cases of bile duct carcinomas, 15 cases of gallbladder carcinomas, 5 cases of pancreaticobiliary malformations and 4 cases of gallbladder adenomas were collected. Using LC-MS analysis, 42 proteins were detected only in gallbladder cancer, 53 proteins in gallbladder adenoma, 39 proteins in pancreaticobiliary malformation and 217 proteins both in cholecystitis and gallbladder cancer.

Free Research Field

人体病理学

URL: 

Published: 2018-03-22  

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