2016 Fiscal Year Final Research Report
Proteomic analysis of bile
Project/Area Number |
26460426
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Human pathology
|
Research Institution | St. Marianna University School of Medicine (2016) Kitasato University (2014-2015) |
Principal Investigator |
|
Co-Investigator(Renkei-kenkyūsha) |
KODERA YOSHIO 北里大学, 理学部, 准教授 (60265733)
|
Project Period (FY) |
2014-04-01 – 2017-03-31
|
Keywords | 胆嚢癌 / 胆嚢炎 / 発癌 / プロテオミクス |
Outline of Final Research Achievements |
The bile and tissue samples including 204 cases of chronic cholecystitis, 30 cases of bile duct carcinomas, 15 cases of gallbladder carcinomas, 5 cases of pancreaticobiliary malformations and 4 cases of gallbladder adenomas were collected. Using LC-MS analysis, 42 proteins were detected only in gallbladder cancer, 53 proteins in gallbladder adenoma, 39 proteins in pancreaticobiliary malformation and 217 proteins both in cholecystitis and gallbladder cancer.
|
Free Research Field |
人体病理学
|