2016 Fiscal Year Final Research Report
Search for RNA biomerker of cardiovascular disease
Project/Area Number |
26460646
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Laboratory medicine
|
Research Institution | University of Yamanashi |
Principal Investigator |
|
Project Period (FY) |
2014-04-01 – 2017-03-31
|
Keywords | RNA診断 / バイオマーカー / 虚血性心疾患 |
Outline of Final Research Achievements |
To identify novel mRNA biomarker from peripheral blood for ischemic heart disease, mRNA expression pattern was compared with patients with normal coronary and patients with acute coronary syndrome. On TLR2, TLR4, CCR2,Annexin A1, FPR2, and TREM1 mRNA, expression levels were statistically different between patients with normal coronary and patients with acute coronary syndrome. The first to third genes were already reported well, however forth to sixth genes are not yet less reported. The Annexin A1, FPR2, and TREM1 mRNA from human peripheral blood might be useful biomarker for ischemic heart disease.
|
Free Research Field |
循環器内科学
|