The association between baseline fatty acid composition of serum lipids and lifestyle-related diseases in the prospective cohort study

2016 Fiscal Year Final Research Report

• Project/Area Number: 26460752
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Epidemiology and preventive medicine
• Research Institution: Osaka City University
• Principal Investigator: SATO KYOKO 大阪市立大学, 大学院医学研究科, 准教授 (00381989)
• Project Period (FY): 2014-04-01 – 2017-03-31
• Keywords: 疫学 / 脂肪酸 / 生活習慣病

Outline of Final Research Achievements

In the prospective cohort study to examine the association between visceral adiposity measured by computed tomography (CT) and lifestyle-related diseases, we measured baseline fatty acid composition of serum lipids.
We cross-sectionally examined the association between baseline fatty acid composition of serum lipids and the prevalence of lifestyle-related diseases or body fat distribution using multivariate analyses. The elevated palmitic acid level was associated with the high prevalence of diabetes. Among men, the elevated dihomo-γ-linolenic acid level was positively associated with abdominal subcutaneous fat area and intra-abdominal fat area. We prospectively examined the association between baseline fatty acid composition of serum lipids and the incidence of lifestyle-related diseases using multivariate analyses. The elevated oleic acid level at baseline was positively associated with the incidence of diabetes.

Free Research Field

医歯薬学