Economic Evaluation of Immunisation Programme of PPSV-23 and the Inclusion of PCV-13 in the List for Single-Dose Subsidy to the Elderly in Japan.

2016 Fiscal Year Final Research Report

• Project/Area Number: 26460824
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Hygiene and public health
• Research Institution: University of Tsukuba
• Principal Investigator: OKUBO Ichiro 筑波大学, 医学医療系, 教授 (40323307)
• Project Period (FY): 2014-04-01 – 2017-03-31
• Keywords: 予防接種 / ワクチン / 肺炎球菌 / 費用効果分析 / 費用効用分析 / 経済評価

Outline of Final Research Achievements

We performed economic evaluations to investigate the efficiency of inclusion of PCV-13 in the list for single-dose pneumococcal vaccine immunisation programme. We constructed a Markov model depicting the S.pneumoniae-related disease course pathways. Cost of per shot of vaccine was \8,116 for PPSV-23 and \10,776 for PCV-13.
Compared to current PPSV-23 strategy, PCV-13 inclusion into the list for single-dose pneumococcal vaccine immunization programme has an ICER of \379,000 per QALY gained regardless of the PCV-13 diffusion level. This ICERs were found to be cost-effective since they are lower than the suggested criterion by WHO of three times GDP.

Free Research Field

保健医療政策学