2016 Fiscal Year Final Research Report
ChinesePlex: A method for differentiation of Japanese and Chinese using Chinese-specific alleles
| Project/Area Number |
26460878
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Legal medicine
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| Research Institution | Tottori University |
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Principal Investigator |
Yuasa Isao 鳥取大学, 医学部, 特任教授 (00093633)
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| Co-Investigator(Renkei-kenkyūsha) |
AKANE Atsushi 関西医科大学, 医学部, 教授 (70202520)
ISHIKAWA Takaki 大阪市立大学, 医学部, 教授 (50381984)
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Keywords | 中国人 / 日本人 / 特異遺伝子 / 個人識別 / PCR / DNA解析 |
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| Outline of Final Research Achievements |
To find out Chinese-specific alleles, 282 candidate SNPs chosen from the 1000 genomes database were investigated in 875 DNA samples from nine East Asian, African, and European populations. Of 177 amplified SNPs showing polymorphisms, 160 derived alleles were detected in Japanese populations. The remaining 17 alleles were observed not only in Chinese but also in other East Asians except for Japanese, indicating the derived alleles were Continent-specific alleles. Because they are not adequate for demonstration that a forensic sample came from a Chinese, they were incorporated into JapanesePlex single base extension method.
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| Free Research Field |
法医学
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