Non-celiac gluten sensitivity and celiac disease

2016 Fiscal Year Final Research Report

• Project/Area Number: 26460980
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Gastroenterology
• Research Institution: National Defense Medical College
• Principal Investigator: Watanabe Chikako 防衛医科大学校(医学教育部医学科進学課程及び専門課程、動物実験施設、共同利用研究, 内科学, 講師 (90365263)
• Project Period (FY): 2014-04-01 – 2017-03-31
• Keywords: 下部消化管学 / 粘膜免疫 / セリアック病 / グルテン / 過敏性腸症

Outline of Final Research Achievements

Celiac disease is precipitated, in genetically predisposed persons, by the ingestion of gluten, resulting in mucosal inflammation and villous atrophy.
“non-celiac gluten sensitivity” is a syndrome characterized by intestinal symptoms related to the ingestion of gluten-containing food, without enteropathy. Not only celiac disease but non-celiac gluten sensitivity sometimes share the similar symptoms to those in irritable bowel syndrome, being possibly misdiagnosed.

Free Research Field

医歯薬学