Prognostic impact of left atrial strain in patients with heart failure with preserved ejection fraction

2016 Fiscal Year Final Research Report

• Project/Area Number: 26461063
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Cardiovascular medicine
• Research Institution: Shinshu University
• Principal Investigator: MOTOKI Hirohiko 信州大学, 学術研究院医学系(医学部附属病院), 講師 (50532058)
• Project Period (FY): 2014-04-01 – 2017-03-31
• Keywords: 心不全 / 左室駆出率保持 / 高齢者 / 心房機能

Outline of Final Research Achievements

414 patients were enrolled in this study. Median age was 81 years, and mean left ventricular ejection fraction was 48%. Approximately 50% of patients showed preserved ejection fraction (LVEF>50%). Primary end-point was composite of all cause death, non-fatal myocardial infarction, non-fatal stroke, and unexpected admission for heart failure. Patients are going to be followed up for 3 years.
In this study, more females with preserved ejection fraction were affected heart failure in octogenarians. Anemia, renal insufficiency, and increased arterial stiffness were evident in our population.

Free Research Field

心不全