2016 Fiscal Year Final Research Report
Postoperative changes in cerebral metabolites associated with cognitive dysfunction after cardiovascular surgery: a diffusion tensor magnetic resonance imaging study and cerebral blood flow imaging
| Project/Area Number |
26461084
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Cardiovascular medicine
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| Research Institution | Iwate Medical University |
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Principal Investigator |
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Keywords | 高次脳機能障害 / 心臓大血管手術 / 脳分子イメージング |
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| Outline of Final Research Achievements |
We considered whether it was related to an appearance of postoperative cognitive dysfunction under the off-pump cardiovascular surgery or cardiopulmonary bypass surgery, hypothermia circulatory arrest surgery, during a slight brain damage on the nervous system. A decline of the transient cognition function was admitted in hypothermia circulatory arrest. The spread abnormality of brain damage wasn't admitted by fractional anisotropy (FA) value by diffusion tensor imaging of MRI, but broad transient spread abnormality has occurred to the cerebral white matter after cardiopulmonary bypass surgery by an analysis using the spread kurtosis picture: diffusion kurtosis imaging (DKI) detected in mean kurtosis (MK) .But the spread abnormality wasn't also admitted using DKI under the off-pump cardiovascular surgery
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| Free Research Field |
心臓血管外科学
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