Iron status and cytokine profile in pulmonary MAC disease

2016 Fiscal Year Final Research Report

• Project/Area Number: 26461157
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Respiratory organ internal medicine
• Research Institution: Niigata University
• Principal Investigator: Moro Hiroshi 新潟大学, 医歯学総合病院, 助教 (40509452)
• Project Period (FY): 2014-04-01 – 2017-03-31
• Keywords: 肺MAC症 / 鉄

Outline of Final Research Achievements

Patients with fibrocavitary MAC lung disease tend to have elevated inflammatory markers, poor nutritional status and deterioration of iron status, and long-term management is necessary. Serum IP-10 levels were significantly increased in the cavitary form, and it is significantly correlated with CRP, Fe, pre-Alb. With prolonged pro-inflammatory state of pulmonary MAC disease, IP-10 might associated with comorbid poor nutritional status and deterioration of iron status, and it might reflect the disease forms and severity of pulmonary MAC disease, as well as pulmonary tuberculosis.

Free Research Field

感染症内科