2017 Fiscal Year Final Research Report
Biennial epidemics and clinical features of influenza C virus infections.
| Project/Area Number |
26461563
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Pediatrics
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| Research Institution | Yamagata University |
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Principal Investigator |
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| Project Period (FY) |
2014-04-01 – 2018-03-31
|
| Keywords | C型インフルエンザウイルス / 抗原変異 / 抗体保有率 / 小児肺炎 |
|---|
| Outline of Final Research Achievements |
Epidemics of influenza C virus infection occurred in Yamagata, in 2014 and 2016, but we could not detect antigenic changes of viruses during a study period. Annual investigation of seroprevalence revealed that the prevalence of the antibodies against influenza C virus in 2015 and 2017 were similar to those in 2014 and 2016, suggesting that influenza C virus had been circulating asymptomatically in 2015 and 2017. Influenza C virus infections in a hospital setting had similar rate of pneumonia, significantly lower frequency of wheezing, and higher levels of WBC and C-reactive protein than human metapneumovirus (hMPV) infection, suggesting that bacterial coinfections make respiratory conditions more severe.
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| Free Research Field |
小児感染症学
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