2017 Fiscal Year Final Research Report
The analysis of pathogenic mechanism of human papilloma virus;related skin neoplasm by using new strategies.
| Project/Area Number |
26461674
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Dermatology
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| Research Institution | Hirosaki University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
澤村 大輔 弘前大学, 医学研究科, 教授 (60196334)
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| Project Period (FY) |
2014-04-01 – 2018-03-31
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| Keywords | 乳頭腫ウイルス / 悪性腫瘍 / DNA |
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| Outline of Final Research Achievements |
The purposes of this research are to analyze the mechanisms of carcinogenesis related to human papilloma virus infection. In HPV-related skin neoplasms, we elucidated the typing of high-risk HPV, the insertion of HPV to chromosome, the relationship between pathophisiology and mutation of cancer-associated gene by using new strategies including smartAmp, APOT assay and TruSeq Amplicon Cancer Panel. Also, we analyzed that how the metylation of HPV influence pathophisiology of HPV-related skin neoplasms.
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| Free Research Field |
皮膚科学
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