2016 Fiscal Year Final Research Report
Basic and clinical study of functional evaluation using 4-dimensional CT
| Project/Area Number |
26461806
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Radiation science
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| Research Institution | Keio University |
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Principal Investigator |
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| Co-Investigator(Renkei-kenkyūsha) |
SAKAMOTO Yoshiaki 慶應義塾大学, 医学部, 助教 (10464835)
OBARA Hideaki 慶應義塾大学, 医学部, 助教 (20276265)
MIZUNO Ryuichi 慶應義塾大学, 医学部, 助教 (60383824)
MAEKAWA Yuichirou 慶應義塾大学, 医学部, 講師 (90296575)
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Keywords | 4次元CT / 面検出器CT / 鼻咽頭機能 / エンドリーク / 排尿機能 / 関節運動 |
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| Outline of Final Research Achievements |
For fundamental analysis, we took 4D-CT to measure the flow velocity of vascular phantom. The measurements had a linear correlation to those taken by Doppler US, which helped to indicate potential use of 4D-CT in measuring flow velocity.
In regards to clinical application, we evaluated the usefulness of 4D-CT in four clinical fields. In otolaryngology, 4D-CT provided quantitative data of the regurgitated area, which will enable the replacement of conventional X-ray and invasive laryngoscopy. In cardiology, 4D-CT data showed higher diagnostic accuracy compared to conventional CT for the evaluation of endoleak after vascular stentgraft, which will help to decrease the use of invasive angiography. In urology, 4D-CT scans taken during the bladder voiding process allows visualization and clarification of the cause of obstruction in patients with dysuria. In orthopedics, with 4D-CT we could achieve quantitative analysis of joint movement, which has been difficult using X-ray.
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| Free Research Field |
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