The accuracy of new diagnostic modality for the diagnosis of colorectal tumors

2016 Fiscal Year Final Research Report

• Project/Area Number: 26461815
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Radiation science
• Research Institution: National Cancer Center Japan
• Principal Investigator: Kakugawa Yasuo 国立研究開発法人国立がん研究センター, 中央病院, 医長 (00537889)
• Project Period (FY): 2014-04-01 – 2017-03-31
• Keywords: 大腸カプセル内視鏡 / 感度 / 平坦型腫瘍

Outline of Final Research Achievements

We conducted a multicenter study to clarify the accuracy of colon capsule endoscopy as new diagnostic modality for the diagnosis of colorectal tumors (in particular, flat or depressed lesions). In this study, colon capsule endoscopy was shown to have 94% sensitivity (62/66). The relative sensitivity of colon capsule endoscopy compared to traditional total colonoscopy was 1.43 (165/115) in protruded lesion and 1.58 (82/52) in flat or depressed lesion. Then, we investigated the detection rate of colorectal lesions using dual camera devices equipped by colon capsule endoscopy in comparison with theological single camera devices. The dual camera increased the detection rate for flat or depressed lesion by a factor of 1.6-1.8 times higher when compared to a theological single camera. Our study revealed that colon capsule endoscopy has enough sensitivity for use in patients suspected of having flat or depressed lesions.

Free Research Field

カプセル内視鏡