Percutaneous cryoablation for benign prostatic hyperplasia: analysis of effects on adjacent organs and surrounding tissues

2017 Fiscal Year Final Research Report

• Project/Area Number: 26461867
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Radiation science
• Research Institution: Kyoto Prefectural University of Medicine
• Principal Investigator: Tanaka Osamu 京都府立医科大学, 医学(系)研究科(研究院), 客員講師 (70317246)
• Co-Investigator(Kenkyū-buntansha): 一条 祐輔 京都府立医科大学, 医学(系)研究科(研究院), 助教 (10714686) ; 田中 匡 京都府立医科大学, 医学(系)研究科(研究院), 助教 (60750544) ; 林 奈津子 京都府立医科大学, 医学(系)研究科(研究院), 客員講師 (70736173) ; 三浦 寛司 京都府立医科大学, 医学(系)研究科(研究院), 助教 (20607593) ; 岡本 芳晴 鳥取大学, 農学部, 教授 (50194410)
• Project Period (FY): 2014-04-01 – 2018-03-31
• Keywords: 凍結療法 / 前立腺 / IVR

Outline of Final Research Achievements

We conducted fundamental research on cryotherapy that is expected to be applied to benign prostatic hyperplasia. Under general anesthesia, a cryoablation to normal prostate was performed for six dogs. MRI was performed before and after freezing, and changes in prostate volume and histopathological changes after cryotherapy were examined. Cryotherapy for the prostate was found to cause severe hemorrhagic necrosis. In addition, when the urethra was in contact with the freezing region, the urethral epithelium was pathologically histologically dropped, but it was impossible to evaluate urethral damage during MRI.

Free Research Field

IVR　腹部画像診断