2016 Fiscal Year Final Research Report
Development of TACE using drug eluting microspheres for HCC
| Project/Area Number |
26461868
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Radiation science
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| Research Institution | Nara Medical University |
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Principal Investigator |
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| Co-Investigator(Renkei-kenkyūsha) |
HIRAI Toshiko 奈良県立医科大学, 医学部, 病院教授 (00208802)
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Keywords | chemoemboliztaion / liver cancer |
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| Outline of Final Research Achievements |
Transarterial chemoembolization (TACE) is widely used for unresectable hepatocellular carcinoma. Recently, TACE using microspheres has been developed. In this study, in a rabbit liver tumor model, TACE using microspheres was evaluated. When comparing TACE using starch microspheres mixed with cisplatin arterial infusion, TACE was superior in the tumor drug concentration and the efficacy. In addition, microspheres dissolved within 24 hours.
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| Free Research Field |
interventional radiology
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