2017 Fiscal Year Final Research Report
A study of tumor diagnosis by whole-body dynamic imaging using positron emission tomography with continuous bed motion.
| Project/Area Number |
26461869
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Radiation science
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| Research Institution | Juntendo University (2016-2017)
Keio University (2014-2015) |
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Principal Investigator |
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| Project Period (FY) |
2014-04-01 – 2018-03-31
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| Keywords | ポジトロンCT / PET/CT / ダイナミック撮像 / FDG / 連続寝台移動 / 腫瘍診断 / 時間放射能曲線 / 生理的集積 |
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| Outline of Final Research Achievements |
Conventional PET image is usually obtained as “static” distribution of radiopharmaceuticals in the body. We newly developed “whole-body dynamic imaging (WBDI)” protocol using continuous bed motion PET scanner that enable us to analyze a change of distribution of radiopharmaceuticals according to time. The object is to discuss whether the method may useful for cancer diagnosis. At first, phantom study was performed to establish a feasible protocol to acquire WBDI, followed by studying for clinical application. In result, no significant difference was found for qualitative diagnosis using WBDI as long as image acquisition was started 1hour post injection, though it may effective for differentiate physiological uptake from pathological accumulation.
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| Free Research Field |
医歯薬学
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