2017 Fiscal Year Final Research Report
New strategy for hypothyroidism with use of regenerative medicine.
| Project/Area Number |
26461950
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
General surgery
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| Research Institution | Nagasaki University |
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Principal Investigator |
MINAMI Shigeki 長崎大学, 医歯薬学総合研究科(医学系), 客員研究員 (90398165)
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| Co-Investigator(Kenkyū-buntansha) |
崎村 千香 長崎大学, 病院(医学系), 助教 (00567175)
山之内 孝彰 長崎大学, 医歯薬学総合研究科(医学系), 講師 (10448508)
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| Project Period (FY) |
2014-04-01 – 2018-03-31
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| Keywords | 甲状腺細胞シート |
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| Outline of Final Research Achievements |
1. We successfully fabricated cell sheets with using thyroid cell of resected human thyroid tissues. 2. These cell sheets expressed thyroid cell-specific markers, i. e., TTF1、TG. Furthermore, cultured thyroid cells produced and secreted thyroid hormone in culture medium. 3. Multilayer thyroid cell sheets with fibroblasts (human TIG118) did not show increase in thyroid hormone production compared to monolayer thyroid cell sheets.
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| Free Research Field |
乳腺内分泌外科学
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