2016 Fiscal Year Final Research Report
Clinical significance and molecular mechanism elucidation of E-cadherin expression in triple-negative breast cancer
| Project/Area Number |
26461957
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| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
General surgery
|
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| Research Institution | Osaka City University |
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Principal Investigator |
|
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| Project Period (FY) |
2014-04-01 – 2017-03-31
|
| Keywords | トリプルネガティブ乳癌 / 個別化治療 / 上皮間葉転換 / E-cadherin |
|---|
| Outline of Final Research Achievements |
Triple-negative breast cancer (TNBC), a subtype of breast cancer that is estrogen receptor (ER)-negative, progesterone receptor (PR)-negative, and human epidermal growth factor receptor 2 (HER2)-negative, has a poor prognosis. Recent research indicates that TNBC can be categorized into seven specific subcategories based on genetic expression profiles. In this study, we showed the possibility of a new therapeutic strategy for TNBC.
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| Free Research Field |
乳腺腫瘍学
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